HG-10-102-01
Cat. No.：YN280058
CAS No. ：1351758-81-0
| 产品名称: | HG-10-102-01 |
| CAS No.: | 1351758-81-0 |
| Chemical Name: | [4-[[5-chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone |
| Synonyms: | [4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮 |
| 分子量: | 377.83 |
| 分子式: | C₁₇H₂₀ClN₅O₃ |
| SMILES: | COC1=CC(C(N2CCOCC2)=O)=CC=C1NC3=NC(NC)=C(Cl)C=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | HG-10-102-01是野生型LRRK2和突变型G2019S抑制剂，IC50分别为23.3 nM和3.2 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Choi, H.G., Zhang, J., Deng, X., et al.Brain Penetrant LRRK2 InhibitorACS Med. Chem. Lett.3(8),658-662(2012)
