GNE-7915
Cat. No.：YN280104
CAS No. ：1351761-44-8
| 产品名称: | GNE-7915 |
| CAS No.: | 1351761-44-8 |
| Chemical Name: | [4-[[4-(ethylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro-5-methoxyphenyl]-4-morpholinyl-methanone |
| Synonyms: | GNE7915 |
| 分子量: | 443.40 |
| 分子式: | C₁₉H₂₁F₄N₅O₃ |
| SMILES: | CCNC1=NC(NC2=C(OC)C=C(C(N3CCOCC3)=O)C(F)=C2)=NC=C1C(F)(F)F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GNE-7915是高效选择性，可渗透大脑的LRRK2抑制剂，IC50值为9 nM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Estrada, A.A., Chan, B.K., Baker-Glenn, C., et al.Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitorsJ. Med. Chem.57(3),921-936(2014)
