Montelukast
Cat. No.：YN320725
| 产品名称: | Montelukast |
| CAS No.: | 158966-92-8 |
| Chemical Name: | 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-cyclopropaneacetic acid |
| Synonyms: | MK0476 free base |
| 分子量: | 586.18 |
| 分子式: | C₃₅H₃₆ClNO₃S |
| SMILES: | O=C(O)CC1(CS[C@@H](C2=CC=CC(/C=C/C3=NC4=CC(Cl)=CC=C4C=C3)=C2)CCC5=CC=CC=C5C(C)(O)C)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Montelukast 是一种有效的、选择性和具有口服活性的半胱氨酸白三烯受体1 (CysLT1)拮抗剂。Montelukast 可用于研究预防哮喘和肝损伤。Montelukast 在肠缺血-再灌注损伤中也具有抗氧化作用，还可以减少心脏损伤。 |
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Cabré, F., Carabaza, A., García, A.M., et al.Pharmacological profile of MEN91507, a new CysLT1 receptor antagonistEur. J. Pharmacol.451(3),317-326(2002)
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