Amelubant
Cat. No.：YN321213
| 产品名称: | Amelubant |
| CAS No.: | 346735-24-8 |
| Chemical Name: | |
| Synonyms: | BIIL 284 |
| 分子量: | 538.63 |
| 分子式: | C₃₃H₃₄N₂O₅ |
| SMILES: | CC(C1=CC=C(OCC2=CC(COC3=CC=C(C(NC(OCC)=O)=N)C=C3)=CC=C2)C=C1)(C4=CC=C(O)C=C4)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Amelubant (BIIL 284) 是一种有效、可口服、长效的LTB4receptor拮抗剂，对 LTB4受体的结合亲和性很低，在细胞和细胞膜中，Ki值分别为 221 nM 和 230 nM。Amelubant (BIIL 284) 是活性代谢物 BIIL 260 和 BIIL 315 的前体。具有抗炎活性。 |
| IC50和靶点: | [{name:"LTB4:221 nM (Ki, in vital human granulocytes)"},{name: "LTB4:230 nM (Ki, in cell membranes)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
