Pranlukast hemihydrate
Cat. No.:YN321445
产品名称: | Pranlukast hemihydrate |
CAS No.: | 150821-03-7 |
Chemical Name: | |
Synonyms: | 普鲁司特半水合物; ONO-1078 hemihydrate |
分子量: | 490.51 |
分子式: | C₂₇H₂₃N₅O₄.₁/₂H₂O |
SMILES: | O=C(C1=CC=C(OCCCCC2=CC=CC=C2)C=C1)NC3=C4C(C(C=C(C5=NN=NN5)O4)=O)=CC=C3.[1/2].O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Pranlukast hemihydrate (ONO-1078 hemihydrate) 是一种高效的竞争性的选择性leukotriene拮抗剂。Pranlukast 抑制 [3H]LTE4,[3H]LTD4和 [3H]LTC4与肺膜结合,Ki分别为 0.63±0.11,0.99±0.19 和 5640±680 nM。 |
IC50和靶点: | [{name:"LTE4:0.63 nM (Ki)"},{name: "LTD4:0.99 nM (Ki)"},{name: "LTC4:5640 nM (Ki)"}] |
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In Vivo: | |
Clinical Trial: | |
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