11-Keto-beta-boswellic acid
Cat. No.：YN321745
| 产品名称: | 11-Keto-beta-boswellic acid |
| CAS No.: | 17019-92-0 |
| Chemical Name: | (3α,4β)-3-hydroxy-11-oxo-urs-12-en-23-oic acid |
| Synonyms: | 11-Keto-β-boswellic acid |
| 分子量: | 470.68 |
| 分子式: | C₃₀H₄₆O₄ |
| SMILES: | C[C@@]1([C@@]2(CC[C@]3(CC[C@H]([C@@H]([C@]3(C2=C4)[H])C)C)C)C)CC[C@@]5([H])[C@](C(O)=O)(C)[C@H](O)CC[C@]5(C)[C@@]1([H])C4=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) 是一种五环三萜酸，来自俗称印度乳香 (Indian Frankincense) 的乳香树 (Boswellia serrate) 树皮的油树脂。 11-Keto-beta-boswellic acid 具有抗炎活性，主要是由于抑制5-脂氧合酶 (5-lipoxygenase; 5-LOX)，白三烯 (leukotriene)，NF-κB的激活和肿瘤坏死因子 α 的产生。 |
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Ammon, H.P., Safayhi, H., Mack, T., et al.Mechanism of antiinflammatory actions of curcumine and boswellic acidsJ. Ethnopharmacol.38(2-3),113-119(1993)
Safayhi, H., Mack, T., Sabieraj, J., et al.Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenaseJ. Pharmacol. Exp. Ther.261(3),1143-1146(1992)
Mostafa, D.M., Ammar, N.M., Basha, M., et al.Transdermal microemulsions of Boswellia carterii Bird: Formulation, characterization and in vivo evaluation of anti-inflammatory activityDrug Deliv.22(6),748-756(2015)
Wang, Q., Pan, X., Wong, H.H., et al.Oral and topical boswellic acid attenuates mouse osteoarthritisOsteoarthritis Cartilage22(1),128-132(2014)
