Iberdomide
Cat. No.:YN430003
产品名称: | Iberdomide |
CAS No.: | 1323403-33-3 |
Chemical Name: | 3S-[1,3-dihydro-4-[[4-(4-morpholinylmethyl)phenyl]methoxy]-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione |
Synonyms: | CC-220 |
分子量: | 449.50 |
分子式: | C₂₅H₂₇N₃O₅ |
SMILES: | O=C([C@@H](N(CC1=C2C=CC=C1OCC3=CC=C(CN4CCOCC4)C=C3)C2=O)CC5)NC5=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Iberdomide (CC-220) 是cereblon (CRBN)调节剂,IC50值为 60 nM。 |
IC50和靶点: | |
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Matyskiela, M.E., Zhang, W., Man, H.W., et al.A cereblon modulator (CC-220) with improved degradation of Ikaros and AiolosJ. Med. Chem.,(2017)