CC-885
Cat. No.:YN430004
产品名称: | CC-885 |
CAS No.: | 1010100-07-8 |
Chemical Name: | N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-urea |
Synonyms: | |
分子量: | 440.88 |
分子式: | C₂₂H₂₁ClN₄O₄ |
SMILES: | O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CC-885 是CRBN蛋白的调节剂,有潜在的抗肿瘤活性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Matyskiela, M.E., Lu, G., Ito, T., et al.A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligaseNature535(7611),252-257(2016)