N-Deshydroxyethyl Dasatinib
Cat. No.:YN430034
产品名称: | N-Deshydroxyethyl Dasatinib |
CAS No.: | 910297-51-7 |
Chemical Name: | N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino]-5-thiazolecarboxamide; Dasatinib metabolite M4; |
Synonyms: | N-Deshydroxyethyl BMS-354825 |
分子量: | 443.95 |
分子式: | C₂₀H₂₂ClN₇OS |
SMILES: | O=C(C1=CN=C(NC2=NC(C)=NC(N3CCNCC3)=C2)S1)NC4=C(C)C=CC=C4Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) 是一种基于 Dasatinib (ABL 抑制剂) 的配体,可通过 linker 与 IAP 配体结合从而形成 SNIPER 分子,从而降解 ABL。 |
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Trentham, D., et al.: Biochem. J., 126, 635