SirReal1-O-propargyl
Cat. No.：YN430036
CAS No. ：1862237-99-7
规格
价格(RMB)
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| 产品名称: | SirReal1-O-propargyl |
| CAS No.: | 1862237-99-7 |
| Chemical Name: | |
| Synonyms: | PROTAC Sirt2-binding moiety 1 |
| 分子量: | 424.54 |
| 分子式: | C₂₁H₂₀N₄O₂S₂ |
| SMILES: | O=C(NC1=NC=C(CC2=CC=CC(OCC#C)=C2)S1)CSC3=NC(C)=CC(C)=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SirReal1-O-propargyl 是Sirtuin 2 (Sirt2)选择性的、强效抑制剂，IC50值为 2.4 μM。SirReal1-O-propargyl 是一种基于 SirReal1的配体，可通过 linker 与 cereblon 配体结合形成 PROTAC分子，从而降解Sirt2。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
