Palbociclib-propargyl
Cat. No.:YN430157
产品名称: | Palbociclib-propargyl |
CAS No.: | 2366269-23-8 |
Chemical Name: | |
Synonyms: | PROTAC CDK6 ligand 1 |
分子量: | 485.58 |
分子式: | C₂₇H₃₁N₇O₂ |
SMILES: | O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCN(CC#C)CC4)C=C3)N=C2N1C5CCCC5 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Palbociclib-propargyl 是一种 PROTAC 靶蛋白CDK6的配体,可通过 PEG linker 与 CRBN 配体结合,组成 PROTAC CP-10。CP-10 可降解 CDK6,DC50值 为 2.1 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |