MALT1 inhibitor MI-2
Cat. No.：YN370956
CAS No. ：1047953-91-2
| 产品名称: | MALT1 inhibitor MI-2 |
| CAS No.: | 1047953-91-2 |
| Chemical Name: | 2-chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl]phenyl]-acetamide |
| Synonyms: | MI 2 (MALT1 inhibitor),MALT1 inhibitor,MI 2 |
| 分子量: | 455.72 |
| 分子式: | C₁₉H₁₇Cl₃N₄O₃ |
| SMILES: | O=C(NC1=CC=C(N2N=C(OCCOC)N=C2C3=CC=C(Cl)C(Cl)=C3)C=C1)CCl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MALT1 inhibitor MI-2 是一种MALT1抑制剂 (IC50=5.84 μM)，MALT1 inhibitor MI-2 直接与 MALT1 结合，不可逆地抑制蛋白酶功能，并伴有 NF-κB 报告子活性抑制、c-REL 核定位抑制和 NF-κB 靶基因下调。MALT1 inhibitor MI-2 对动物无毒。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Fontan, L., Yang, C., Kabaleeswaran, V., et al.MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivoCancer Cell.22(6),812-824(2012)
