DLK-IN-1
Cat. No.：YN350086
CAS No. ：1620574-24-4
| 产品名称: | DLK-IN-1 |
| CAS No.: | 1620574-24-4 |
| Chemical Name: | |
| Synonyms: | DLK inhibitor 14;MAP3K12-IN-14 |
| 分子量: | 423.43 |
| 分子式: | C₂₀H₂₄F₃N₅O₂ |
| SMILES: | CC(N1C([C@@H]2[C@]3([H])[C@@]2([H])CN(C4COC4)C3)=CC(C5=CN=C(N)C(OC(F)(F)F)=C5)=N1)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | DLK-IN-1 是具有口服活性的双亮氨酸拉链激酶(DLK, MAP3K12)的选择性抑制剂，其Ki值为 3 nM。DLK-IN-1 保持着良好的中枢神经系统穿透能力，并且在脑内剂量过量后依旧耐受性良好，在阿尔兹海默症动物模型中有良好的活性。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
