Cot inhibitor-2
Cat. No.：YN350207
CAS No. ：915363-56-3
| 产品名称: | Cot inhibitor-2 |
| CAS No.: | 915363-56-3 |
| Chemical Name: | |
| Synonyms: | 3-Quinolinecarbonitrile, 8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[[[1-(1-ethyl-4-piperidinyl)-1H-1,2,3-triazol-4-yl]methyl]amino]- |
| 分子量: | 539.43 |
| 分子式: | C₂₆H₂₅Cl₂FN₈ |
| SMILES: | N#CC1=C(C2=CC(NCC3=CN(N=N3)C4CCN(CC4)CC)=CC(Cl)=C2N=C1)NC5=CC=C(F)C(Cl)=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cot inhibitor-2 是一种有效的，选择性的，具有口服活性的cot (Tpl2/MAP3K8)抑制剂，IC50为 1.6 nM。Cot inhibitor-2 抑制 LPS 刺激的人全血中 TNF-α 的产生，IC50为 0.3 μM。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
