NCB-0846
Cat. No.:YN350010
CAS No. :1792999-26-8
产品名称: | NCB-0846 |
CAS No.: | 1792999-26-8 |
Chemical Name: | cis-4-[[2-(1H-benzimidazol-6-ylamino)-8-quinazolinyl]oxy]-cyclohexanol |
Synonyms: | NCB 0846 |
分子量: | 375.42 |
分子式: | C₂₁H₂₁N₅O₂ |
SMILES: | O[C@@H](CC1)CC[C@@H]1OC2=CC=CC(C=N3)=C2N=C3NC4=CC=C(N=CN5)C5=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | NCB-0846是具有口服活性的TNIK抑制剂,IC50值为21 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Masuda, M., Uno, Y., Ohbayashi, N., et al.TNIK inhibition abrogates colorectal cancer stemnessNat. Commun.7,12586(2016)