CMPD1
Cat. No.:YN350058
CAS No. :41179-33-3
产品名称: | CMPD1 |
CAS No.: | 41179-33-3 |
Chemical Name: | 2'-fluoro-N-(4-hydroxyphenyl)-[1,1'-biphenyl]-4-butanamide |
Synonyms: | CMPD 1;CMPD1 |
分子量: | 349.40 |
分子式: | C₂₂H₂₀FNO₂ |
SMILES: | O=C(NC1=CC=C(O)C=C1)CCCC2=CC=C(C3=CC=CC=C3F)C=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CMPD1 是一种选择性且非 ATP 竞争性的 p38 MAPK 介导的MK2磷酸化抑制剂,表观Ki(Kiapp)值为 330 nM。 |
IC50和靶点: | |
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Solvent & Solubility: |
Davidson, W., Frego, L., Peet, G.W., et al.Discovery and characterization of a substrate selective p38α inhibitorBiochemistry43(37),11658-11671(2004)
Brennan, P.E.Deciphering the true antiproliferative target of an MK2 activation inhibitor in glioblastomaCell Death Dis.e2069,(2016)