MK2-IN-1 hydrochloride
Cat. No.:YN350123
CAS No. :1314118-94-9
产品名称: | MK2-IN-1 hydrochloride |
CAS No.: | 1314118-94-9 |
Chemical Name: | 5-(4-chlorophenyl)-N-[4-(1-piperazinyl)phenyl]-N-(2-pyridinylmethyl)-2-furancarboxamide, monohydrochloride |
Synonyms: | MK2 Inhibitor,MK 25 |
分子量: | 509.43 |
分子式: | C₂₇H₂₆Cl₂N₄O₂ |
SMILES: | O=C(C1=CC=C(C2=CC=C(Cl)C=C2)O1)N(C3=CC=C(N4CCNCC4)C=C3)CC5=NC=CC=C5.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MK2-IN-1 hydrochloride 是MAPKAPK2(MK2)激酶高效选择性抑制剂,IC50值0.11uM。 |
IC50和靶点: | |
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Huang, X., Shipps, G.W., Jr., Cheng, C.C., et al.Discovery and hit-to-lead optimization of non-ATP competitive MK2 (MAPKAPK2) inhibitorsACS Med. Chem. Lett.2(8),632-637(2011)