Mycophenolic acid
Cat. No.:YN372800
产品名称: | Mycophenolic acid |
CAS No.: | 24280-93-1 |
Chemical Name: | (4E)-6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid |
Synonyms: | 霉酚酸; Mycophenolate |
分子量: | 320.34 |
分子式: | C₁₇H₂₀O₆ |
SMILES: | O=C(O)CC/C(C)=C/CC1=C(O)C2=C(COC2=O)C(C)=C1OC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Mycophenolic acid (Mycophenolate) 是免疫抑制剂,有抗增殖活性。 |
IC50和靶点: | |
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Mitsui, A., and Suzuki, S.Immunosuppressive effect of mycophenolic acidJ. Antibiot. (Tokyo)22(8),358-363(1969)
Noto, T., Sawada, M., Ando, K., et al.Some biological properties of mycophenolic acidJ. Antibiot. (Tokyo)22(4),165-169(1969)
Fujiyama, N., Miura, M., Kato, S., et al.Involvement of carboxylesterase 1 and 2 in the hydrolysis of mycophenolate mofetilDrug Metab. Dispos.38(12),2210-2217(2010)
Watkins, W.J., Chen, J.M., Cho, A., et al.Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDHBioorg. Med. Chem. Lett.16(13),3479-3483(2006)
Franklin, T.J., and Cook, J.M.The inhibition of nucleic acid synthesis by mycophenolic acidBiochem J.113(3),515-524(1969)
Williams, R.H., Lively, D.H., DeLong, D.C., et al.Mycophenolic acid: Antiviral and antitumor propertiesJ. Antibiot. (Tokyo)21(7),463-464(1968)