Cobimetinib hemifumarate
Cat. No.:YN350130
产品名称: | Cobimetinib hemifumarate |
CAS No.: | 1369665-02-0 |
Chemical Name: | |
Synonyms: | 考比替尼半富马酸盐; GDC-0973 hemifumarate; XL-518 hemifumarate |
分子量: | 647.38 |
分子式: | C₂₅H₂₅F₃IN₃O₆ |
SMILES: | OC1([C@H]2NCCCC2)CN(C1)C(C3=C(C(F)=C(C=C3)F)NC4=C(C=C(C=C4)I)F)=O.O=C(O)/C=C/C(O)=O.[0.5] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Cobimetinib hemifumarate 是一种有效的具有选择性的MEK1抑制剂,能够抑制MEK1的活性,IC50值为 4.2 nM。 |
IC50和靶点: | [{name:"MEK1:4.2 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |