Isorhamnetin
Cat. No.：YN350235
CAS No. ：480-19-3
| 产品名称: | Isorhamnetin |
| CAS No.: | 480-19-3 |
| Chemical Name: | 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | 异鼠李素; 3'-Methylquercetin |
| 分子量: | 316.26 |
| 分子式: | C₁₆H₁₂O₇ |
| SMILES: | O=C1C(O)=C(C2=CC=C(O)C(OC)=C2)OC3=CC(O)=CC(O)=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Isorhamnetin 是从中草药沙棘 (Hippophae rhamnoidesL.) 中提取的类黄酮化合物。Isorhamnetin 可通过直接抑制MEK1和PI3K来抑制皮肤癌。 |
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Nagao, A., Seki, M., and Kobayashi, H.Inhibition of xanthine oxidase by flavonoidsBiosci. Biotechnol. Biochem.63(10),1787-1790(1999)
Kawasaki, T., Ito, H., and Omote, H.Components of foods inhibit a drug exporter, human multidrug and toxin extrusion transporter 1Biol. Pharm. Bull.37(2),292-297(2014)
Xu, S.L., Choi, R.C.Y., Zhu, K.Y., et al.Isorhamnetin, a flavonol aglycone from Ginkgo biloba L., induces neuronal differentiation of cultured PC12 cells: Potentiating the effect of nerve growth factorEvid. Based Complement. Alternat. Med.,278273(2012)
Sun, J., Sun, G., Meng, X., et al.Isorhamnetin protects against doxorubicin-induced cardiotoxicity in vivo and in vitroPLoS One8(5),1-14(2014)
Ramachandran, L., Manu, K.A., Shanmugam, M.K., et al.Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancerJ. Biol. Chem.287(45),38028-38040(2012)
Saud, S.M., Young, M.R., Jones-Hall, Y.L., et al.Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-cateninCancer Res.73(17),5473-5484(2013)
