MELK-8a hydrochloride
Cat. No.:YN420008
产品名称: | MELK-8a hydrochloride |
CAS No.: | 2096992-20-8 |
Chemical Name: | 1-methyl-4-[4-[4-[3-(4-piperidinylmethoxy)-4-pyridinyl]-1H-pyrazol-1-yl]phenyl]-piperazine, monohydrochloride |
Synonyms: | MELK-8a HCl; MELK-8a HCl; MELK-8a HCl; MELK-8a hydrochloride |
分子量: | 469.02 |
分子式: | C₂₅H₃₃ClN₆O |
SMILES: | CN(CC1)CCN1C2=CC=C(N3C=C(C4=CC=NC=C4OCC5CCNCC5)C=N3)C=C2.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MELK-8a hydrochloride是一种新颖的母体胚胎亮氨酸拉链激酶(MELK)抑制剂,其IC50值为2 nM。 |
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Touré, B.B., Giraldes, J., Smith, T., et al.Toward the validation of maternal embryonic leucine zipper kinase: Discovery, optimization of highly potent and selective inhibitors, and preliminary biology insightJ. Med. Chem.59(10),4711-4723(2016)