Melatonin
Cat. No.：YN321383
| 产品名称: | Melatonin |
| CAS No.: | 73-31-4 |
| Chemical Name: | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-acetamide |
| Synonyms: | 褪黑素; N-Acetyl-5-methoxytryptamine |
| 分子量: | 232.28 |
| 分子式: | C₁₃H₁₆N₂O₂ |
| SMILES: | CC(NCCC1=CNC2=C1C=C(OC)C=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Melatonin 是一种由松果体制成的激素，可激活褪黑激素受体。Melatonin 在睡眠中起作用并具有重要的抗氧化和抗炎特性。Melatonin 是一种新型的选择性ATF-6抑制剂，可通过 COX-2 下调诱导人肝癌细胞凋亡。Melatonin 通过内质网应激减弱palmitic acid-induced (HY-N0830)诱导的小鼠颗粒细胞凋亡。 |
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Boutin, J.A., Audinot, V., Ferry, G., et al.Molecular tools to study melatonin pathways and actionsTrends Pharmacol. Sci.26(8),412-419(2005)
Reiter, R.J., Tan, D.X., Manchester, L.C., et al.Biochemical reactivity of melatonin with reactive oxygen and nitrogen speciesCell Biochem. Biophys.34(2),237-256(2001)
Reiter, R.J., Tang, L., Garcia, J.J., et al.Pharmacological actions of melatonin in oxygen radical pathophysiologyLife Sci.60(25),2255-2271(1997)
