Melatonin D4
Cat. No.：YN321384
| 产品名称: | Melatonin D4 |
| CAS No.: | 66521-38-8 |
| Chemical Name: | N-[2-(5-methoxy-1H-indol-3-yl)ethyl-1,1,2,2-d4]-acetamide |
| Synonyms: | 褪黑素 D5; N-Acetyl-5-methoxytryptamine D4 |
| 分子量: | 236.30 |
| 分子式: | C₁₃H₁₂D₄N₂O₂ |
| SMILES: | CC(NC([2H])([2H])C([2H])([2H])C1=CNC2=C1C=C(OC)C=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Melatonin D4 是Melatonin 的氘代物。Melatonin是一种由松果体制成的激素，可激活褪黑激素受体 (melatonin receptor)。具有抗氧化和抗炎特性。Melatonin 是一种新型的选择性 ATF-6 抑制剂，可通过 COX-2 下调诱导人肝癌细胞凋亡。 |
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Boutin, J.A., Audinot, V., Ferry, G., et al.Molecular tools to study melatonin pathways and actionsTrends Pharmacol. Sci.26(8),412-419(2005)
Reiter, R.J., Tan, D.X., Manchester, L.C., et al.Biochemical reactivity of melatonin with reactive oxygen and nitrogen speciesCell Biochem. Biophys.34(2),237-256(2001)
Reiter, R.J., Tang, L., Garcia, J.J., et al.Pharmacological actions of melatonin in oxygen radical pathophysiologyLife Sci.60(25),2255-2271(1997)
