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Betaine

Cat. No.:YN1720047

  • CAS No. :107-43-7

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Betaine
      CAS No.: 107-43-7
      Chemical Name: 1-carboxy-N,N,N-trimethyl-methanaminium, inner salt
      Synonyms:甜菜碱; Trimethylglycine; carboxy-N,N,N-trimethylmethanaminium
      分子量:117.14638
      分子式:C5H11NO2
      SMILES:[O-]C(C[N+](C)(C)C)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Betaine (Trimethylglycine) 是许多食物中发现的天然化合物,也是一种可维持正常 DNA 甲基化模式的活性甲基供体。Betaine 广泛存在于植物,动物,微生物和丰富的膳食来源中,包括海鲜,菠菜和麦麸。Betaine 也可作为渗透物,通过防止脱水和渗透失活来维持禽类的细胞水和离子平衡,从而提高禽类对热应激的能力。 它有助于维持保护性渗透活性,特别是在热应激的鸟类中。Betaine 可以促进各种肠道微生物抵抗渗透变化,从而改善微生物发酵活性。
      IC50和靶点:
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    • Ueland, P.M.Choline and betaine in health and diseaseJ. Inherit. Metab. Dis.34(1),3-15(2011)

      Veskovic, M., Mladenovic, D., Milenkovic, M., et al.Betaine modulates oxidative stress, inflammation, apoptosis, autophagy, and Akt/mTOR signaling in methionine-choline deficiency-induced fatty liver diseaseEur. J. Pharmacol.848,39-48(2019)

      Maclean, K.N., Sikora, J., Kožich, V., et al.A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatmentMol. Genet. Metab.101(2-3),153-162(2010)

      Sakamoto, A., Nishimura, Y., Ono, H., et al.Betaine and homocysteine concentrations in foodsPediatr. Int.44(4),409-413(2002)

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