Desmosterol
Cat. No.：YN1720061
CAS No. ：313-04-2
| 产品名称: | Desmosterol |
| CAS No.: | 313-04-2 |
| Chemical Name: | (3β)-cholesta-5,24-dien-3-ol |
| Synonyms: | 胆固醇EP杂质B (Desmosterol |
| 分子量: | 384.6 |
| 分子式: | C27H44O |
| SMILES: | C/C(C)=C/CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Desmosterol 是一种类似胆固醇的分子。在胆固醇生物合成的 Bloch 途径中，Desmosterol 是胆固醇的直接前体。Desmosterol 作为内源性代谢物，用于研究胆固醇代谢。 |
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Huster, D., Scheidt, H.A., Arnold, K., et al.Desmosterol may replace cholesterol in lipid membranesBiophys. J.88(3),1838-1844(2005)
Jansen, M., Wang, W., Greco, D., et al.What dictates the accumulation of desmosterol in the developing brain?FASEB J.27(3),865-870(2013)
Clayton, P.T.Disorders of cholesterol biosynthesisArch. Dis. Child.78(2),185-189(1998)
Heverin, M., Meaney, S., Brafman, A., et al.Studies on the cholesterol-free mouse: Strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterolArterioscler. Thromb. Vasc. Biol.27(10),2191-2197(2007)
Spann, N.J., Garmire, L.X., McDonald, J.G., et al.Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responsesCell151(1),138-152(2012)
