Curvulin
Cat. No.:YN290162
产品名称: | Curvulin |
CAS No.: | 19054-27-4 |
Chemical Name: | 2-acetyl-3,5-dihydroxy-benzeneacetic acid, ethyl ester |
Synonyms: | |
分子量: | 238.24 |
分子式: | C₁₂H₁₄O₅ |
SMILES: | O=C(OCC)CC1=CC(O)=CC(O)=C1C(C)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Curvulin 是从Curvularia lunata分离出来的一种植物毒素,据报道 Curvulin 还抑制微管 (microtubule) 组装,还抑制 iNOS 表达。 |
IC50和靶点: | |
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Tadross, P.M., Virgil, S.C., and Stoltz, B.M.Aryne acyl-alkylation in the general and convergent synthesis of benzannulated macrolactone natural products: an enantioselective synthesis of (-)-curvularinOrg. Lett.12(7),1612-1614(2010)
Yao, Y., Hausding, M., Erkel, G., et al.Sporogen, S14-95, and S-curvularin, three inhibitors of human inducible nitric-oxide synthase expression isolated from fungiMol. Pharmacol.63(2),383-391(2003)