10-Oxo Docetaxel
Cat. No.:YN290400
产品名称: | 10-Oxo Docetaxel |
CAS No.: | 167074-97-7 |
Chemical Name: | (αR,βS)-β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-benzenepropanoic acid, (2aR,4S,4aS,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5,6-dioxo-7,11-methano-1H |
Synonyms: | Docetaxel Impurity 1 |
分子量: | 805.86 |
分子式: | C₄₃H₅₁NO₁₄ |
SMILES: | CC(O[C@@]1([C@](C[C@@H]2O)([H])OC1)[C@@]([C@@]2(C3=O)C)([H])[C@@H]([C@@](C4(C)C)(C[C@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)C(C)=C4C3=O)O)OC(C6=CC=CC=C6)=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 10-Oxo Docetaxel (Docetaxel Impurity 1) 是新型紫杉烷,具有明显的抗肿瘤活性,是多西他赛(docetaxel)的中间体。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Malleswara Reddy, A., Banda, N., Govind Dagdu, S., et al.Evaluation of the pharmaceutical quality of docetaxel injection using new stability indicating chromatographic methods for assay and impuritiesSci. Pharm.78(2),215-231(2010)