Combretastatin A4
Cat. No.：YN290517
| 产品名称: | Combretastatin A4 |
| CAS No.: | 117048-59-6 |
| Chemical Name: | 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-phenol |
| Synonyms: | CRC 87-09 |
| 分子量: | 316.35 |
| 分子式: | C₁₈H₂₀O₅ |
| SMILES: | OC1=CC(/C=C\C2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Combretastatin A4 是一种microtubule抑制剂，能够与β-tubulin结合，Kd值为 0.4 μM。 |
| IC50和靶点: | |
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Sun, L., Vasilevich, N.I., Fuselier, J.A., et al.Abilities of 3,4-diarylfuran-2-one analogs of combretastatin A-4 to inhibit both proliferation of tumor cell lines and growth of relevant tumors in nude miceAnticancer Res.24,179-186(2004)
Dey, P.Chromatin remodeling, cancer and chemotherapyCurr. Med. Chem.13,2909-2919(2006)
