(E)-Necrosulfonamide
Cat. No.:YN350008
CAS No. :1360614-48-7
产品名称: | (E)-Necrosulfonamide |
CAS No.: | 1360614-48-7 |
Chemical Name: | |
Synonyms: | (E)-Necrosulfonamide |
分子量: | 461.47 |
分子式: | C₁₈H₁₅N₅O₆S₂ |
SMILES: | O=C(NC1=CC=C(S(=O)(NC2=NC=CN=C2OC)=O)C=C1)/C=C/C3=CC=C([N+]([O-])=O)S3.[(E)] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (E)-Necrosulfonamide,一种necroptosis抑制剂,通过选择性靶向(MLKL)。(E)-Necrosulfonamide 阻止 MLKL-RIP1-RIP3 坏死小体复合体与其下游效应子相互作用。MLKL 是诱导坏死过程中 RIP3 的重要底物。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |