GW806742X
Cat. No.：YN350081
CAS No. ：579515-63-2
| 产品名称: | GW806742X |
| CAS No.: | 579515-63-2 |
| Chemical Name: | |
| Synonyms: | GW806742X;3-(4-(Methyl(4-(3-(4-(trifluoromethoxy)phenyl)ureido)phenyl)amino)pyrimidin-2-ylamino)benzenesulfonamide;1-[4-[methyl-[2-[(3-Sulfamoylphenyl)amino]pyrimidin-4-Yl]amino]phenyl]-3-[4-(Trifluoromethyloxy)phenyl]urea;urea deriv. 23;MLKL compound 1;B |
| 分子量: | 573.55 |
| 分子式: | C₂₅H₂₂F₃N₇O₄S |
| SMILES: | O=S(C1=CC=CC(NC2=NC=CC(N(C)C3=CC=C(NC(NC4=CC=C(OC(F)(F)F)C=C4)=O)C=C3)=N2)=C1)(N)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GW806742X 是一种混合谱系激酶结构域样蛋白(MLKL)抑制剂，结合 MLKL 假激酶域的Kd值为 9.3 μM，并具有抗坏死活性。GW806742X 也具有抗 VEGFR2 的活性。 |
| IC50和靶点: | [{name:"MLKL:9.3 μM (Kd)"},{name: "VEGFR2:2 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
