MAO-IN-M30 dihydrochloride
Cat. No.:YN380072
产品名称: | MAO-IN-M30 dihydrochloride |
CAS No.: | 64821-19-8 |
Chemical Name: | |
Synonyms: | M 30 dihydrochloride |
分子量: | 299.20 |
分子式: | C₁₄H₁₆Cl₂N₂O |
SMILES: | OC1=C2N=CC=CC2=C(CN(C)CC#C)C=C1.[H]Cl.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MAO-IN-M30 dihydrochloride 是一种口服活性,可通过血脑屏障的,脑选择性不可逆MAO-A(IC50=37 nM) 和MAO-B(IC50=57 nM) 抑制剂。MAO-IN-M30 dihydrochloride 是有效的铁螯合剂、自由基清除剂。MAO-IN-M30 dihydrochloride 对 Dexamethasone 诱导的脑细胞凋亡具有神经保护作用。MAO-IN-M30 dihydrochloride 在 MPTP 和 lactacystin 帕金森病模型中也显示出神 |
IC50和靶点: | [{name:"MAO-A:37 nM (IC50)"},{name: "MAO-B:57 nM (IC50)"}] |
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In Vivo: | |
Clinical Trial: | |
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