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Toloxatone

Cat. No.:YN380090

  • CAS No. :29218-27-7

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    • 参考文献
    • 产品名称: Toloxatone
      CAS No.: 29218-27-7
      Chemical Name: 5-(hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone
      Synonyms:托洛沙酮; MD 69276
      分子量:207.23
      分子式:C₁₁H₁₃NO₃
      SMILES:CC1=CC(N2C(OC(CO)C2)=O)=CC=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Toloxatone (MD 69276) 是一种可逆的单胺氧化酶 A (MAOA) 抑制剂。用作抗抑郁剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Cesura, A.M., and Pletscher, A.The new generation of monoamine oxidase inhibitorsProg. Drug Res.38,171-297(1992)

      Keane, P.E., Kan, J.P., Sontag, N., et al.Monoamine oxidase inhibition and brain amine metabolism after oral treatment with toloxatone in the ratJ. Pharm. Pharmacol.31(11),752-754(1979)

      Van der Meersch-Mougeot, V., da Rocha, M., Jr., Monier, C., et al.Benzodiazepines reverse the anti-immobility effect of antidepressants in the forced swimming test in miceNeuropharmacology32(5),439-446(1993)

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