Clorgyline hydrochloride
Cat. No.：YN380091
CAS No. ：17780-75-5
| 产品名称: | Clorgyline hydrochloride |
| CAS No.: | 17780-75-5 |
| Chemical Name: | N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-2-propyn-1-amine, monohydrochloride |
| Synonyms: | Clorgiline hydrochloride,盐酸氯吉林,N-[3-(2,4-二氯苯氧基)丙基]-N-甲基-2-丙炔胺盐酸盐 |
| 分子量: | 308.63 |
| 分子式: | C₁₃H₁₆Cl₃NO |
| SMILES: | C#CCN(CCCOC1=CC=C(Cl)C=C1Cl)C.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Clorgyline hydrochloride 是不可逆的，选择性单胺氧化酶A（MAO-A）抑制剂，结构上与Pargyline相关。 |
| IC50和靶点: | |
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Abdelhafez, O.M., Amin, K.M., Ali, H.I., et al.Synthesis of new 7-oxycoumarin derivatives as potent and selective monoamine oxidase A inhibitorsJ. Med. Chem.55(23),10424-10436(2012)
Mazouz, F., Gueddari, S., Burstein, C., et al.5-[4-(Benzyloxy)phenyl]-1,3,4-oxadiazol-2(3H)-one derivatives and related analogues: New reversible, highly potent, and selective monoamine oxidase type B inhibitorsJ. Med. Chem.36(9),1157-1167(1993)
Pälvimäki, E.P., Roth, B.L., Majasuo, H., et al.Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2C receptorPsychopharmacology (Berl)126(3),234-240(1996)
Ganapathy, M.E., Prasad, P.D., Huang, W., et al.Molecular and ligand-binding characterization of the σ-receptor in the Jurkat human T lymphocyte cell lineJ. Pharmacol. Exp. Ther.289(1),251-260(1999)
La Regina, G., Silvestri, R., Gatti, V., et al.Synthesis, structure-activity relationships and molecular modeling studies of new indole inhibitors of monoamine oxidases A and BBioorg. Med. Chem.16(22),9729-9740(2008)
