Lazabemide hydrochloride
Cat. No.：YN380095
| 产品名称: | Lazabemide hydrochloride |
| CAS No.: | 103878-83-7 |
| Chemical Name: | |
| Synonyms: | Ro 19-6327 hydrochloride |
| 分子量: | 236.10 |
| 分子式: | C₈H₁₁Cl₂N₃O |
| SMILES: | O=C(C1=NC=C(Cl)C=C1)NCCN.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lazabemide hydrochloride (Ro 19-6327 hydrochloride) 是单胺氧化酶 B (MAO-B) 的选择性的可逆抑制剂(IC50=0.03 μM)，但对 MAO-A (IC50>100 μM) 活性较低。高浓度 Lazabemide 具有抑制单胺摄取的作用，抑制去甲肾上腺素、血清素和多巴胺摄取的 IC50值分别为 86 μM、123 μM 和 >500 μM。Lazabemide 可用于帕金森和阿尔茨海默病的研究。 |
| IC50和靶点: | [{name:"MAO-B:0.4 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
