Rasagiline mesylate
Cat. No.:YN380103
CAS No. :161735-79-1
产品名称: | Rasagiline mesylate |
CAS No.: | 161735-79-1 |
Chemical Name: | (1R)-2,3-Dihydro-N-2-propyn-1-yl-1H-inden-1-amine Mesylate; (R)-2,3-Dihydro-N-2-propynyl-1-indenamine Mesylate; Agilect; Azilect; TVP-1012; |
Synonyms: | 甲磺酸雷沙吉兰; AGN1135 mesylate; TVP1012 mesylate |
分子量: | 267.34 |
分子式: | C₁₃H₁₇NO₃S |
SMILES: | CS(=O)(O)=O.C#CCN[C@H]1C2=CC=CC=C2CC1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Rasagiline mesylate 是MAO-B抑制剂,可作用于原发性帕金森病。 |
IC50和靶点: | [{name:"rMAO-B:4.43 nM (IC50)"},{name: "rMAO-A:412 nM (IC50)"}] |
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(1) Rabey, J.M., et al.: Clin. Neuropharmacol., 23, 324 (2000) & (2) Glezer, S., et al.: Eur. J. Pharmacol., 472, 173 (2003) & (3) Youdim, M.B.H., et al.: Biochem. Pharmacol., 66, 1635 (2003) & (4) Chen, J.J., et al.: J. Clin. Pharmacol., 45, 878 (2005)