Mofegiline hydrochloride
Cat. No.：YN380116
CAS No. ：120635-25-8
| 产品名称: | Mofegiline hydrochloride |
| CAS No.: | 120635-25-8 |
| Chemical Name: | 4-fluoro-βE-(fluoromethylene)-benzenebutanamine, monohydrochloride |
| Synonyms: | MDL72974A |
| 分子量: | 233.69 |
| 分子式: | C₁₁H₁₄ClF₂N |
| SMILES: | FC1=CC=C(CC/C(CN)=C(F)/[H])C=C1.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mofegiline hydrochloride (MDL72974A) 是酶活化的不可逆MAO-B抑制剂，对MAO-A和MAO-B的IC50分别为680和3.6 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Zreika, M., Fozard, J.R., Dudley, M.W., et al.MDL 72,974: A potent and selective enzyme-activated irreversible inhibitor of monoamine oxidase type B with potential for use in Parkinson's diseaseJ. Neural Transm. Park. Dis. Dement. Sect.1(4),243-254(1989)
Foot, J.S., Deodhar, M., Turner, C.I., et al.The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1)Bioorg. Med. Chem. Lett.22(12),3935-3940(2012)
