OG-L002
Cat. No.：YN380133
| 产品名称: | OG-L002 |
| CAS No.: | 1357302-64-7 |
| Chemical Name: | 4'-[(1R,2S)-2-aminocyclopropyl]-[1,1'-biphenyl]-3-ol |
| Synonyms: | OGL002,OG L002,OGL-002 |
| 分子量: | 225.29 |
| 分子式: | C₁₅H₁₅NO |
| SMILES: | OC1=CC(C2=CC=C([C@@H]3[C@@H](N)C3)C=C2)=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | OG-L002 是一种有效且高度选择性的LSD1抑制剂，IC50为 0.02 μM。OG-L002 是一种有效的单胺氧化酶 (MAO) 抑制剂，对 MAO-A 和 MAO-B 的IC50分别为 1.38 μM 和 0.72 μM。OG-L002 有效抑制HSV IE基因的表达。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Forneris, F., Binda, C., Vanoni, M.A., et al.Human histone demethylase LSD1 reads the histone codeJ. Biol. Chem.280(50),41360-41365(2005)
Liang, Y., Quenelle, D., Vogel, J.L., et al.A novel selective LSD1/KDM1A inhibitor epigenetically blocks Herpes simplex virus lytic replication and reactivation from latencymBio4(1),1-9(2013)
