Valbenazine
Cat. No.:YN360591
CAS No. :1025504-45-3
产品名称: | Valbenazine |
CAS No.: | 1025504-45-3 |
Chemical Name: | L-valine, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester |
Synonyms: | NBI-98854 |
分子量: | 418.57 |
分子式: | C₂₄H₃₈N₂O₄ |
SMILES: | O=C([C@@H](N)C(C)C)O[C@@H]1C[C@]2([H])C3=CC(OC)=C(OC)C=C3CCN2C[C@H]1CC(C)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Valbenazine (NBI-98854) 是一种囊泡单胺类转运 2 (VMAT2) 抑制剂,Ki为 110-190 nM。 |
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Grigoriadis, D.E., Smith, E., Hoare, S.R.J., et al.Pharmacologic characterization of valbenazine (NBI-98854) and its metabolitesJ. Pharmacol. Exp. Ther.361(3),454-461(2017)