Tetrabenazine D6
Cat. No.：YN360814
CAS No. ：1392826-25-3
| 产品名称: | Tetrabenazine D6 |
| CAS No.: | 1392826-25-3 |
| Chemical Name: | rel-1,3R,4,6,7,11bR-hexahydro-9,10-di(methoxy-d3)-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one |
| Synonyms: | 丁苯那嗪 D6; Ro 1-9569 D6 |
| 分子量: | 323.46 |
| 分子式: | C₁₉H₂₁D₆NO₃ |
| SMILES: | O=C1[C@H](CC(C)C)CN2CCC3=CC(OC([2H])([2H])[2H])=C(OC([2H])([2H])[2H])C=C3[C@@]2([H])C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tetrabenazine D6 是Tetrabenazine 的氘代物。 |
| IC50和靶点: | |
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Erickson, J.D., Schäfer, M.K.H., Bonner, T.I., et al.Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporterProc. Natl. Acad. Sci. USA93(10),5166-5171(1996)
Pettibone, D.J., Totaro, J.A., and Pflueger, A.B.Tetrabenazine-induced depletion of brain monoamines: Characterization and interaction with selected antidepressantsEur. J. Pharmacol.102(3-4),425-430(1984)
Preskorn, S.H., Kent, T.A., Glotzbach, R.K., et al.Cerebromicrocirculatory defects in animal model of depressionPsychoparmacology (Berl).84(2),196-199(1984)
Wang, H., Chen, X., Li, Y., et al.Tetrabenazine is neuroprotective in Huntington's disease miceMol. Neurodegener.5:18,(2010)
