α-Cyano-4-hydroxycinnamic acid
Cat. No.：YN360189
| 产品名称: | α-Cyano-4-hydroxycinnamic acid |
| CAS No.: | 28166-41-8 |
| Chemical Name: | 2-cyano-3-(4-hydroxyphenyl)-2-propenoic acid |
| Synonyms: | α-Cyano-4-hydroxycinnamate |
| 分子量: | 189.17 |
| 分子式: | C₁₀H₇NO₃ |
| SMILES: | O=C(O)/C(C#N)=C/C1=CC=C(O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) 是有效的非竞争性单羧酸盐转运蛋白 (MCTs) 抑制剂。α-Cyano-4-hydroxycinnamic acid 抑制线粒体丙酮酸转运蛋白，Ki值为 6.3 μM。α-Cyano-4-hydroxycinnamic acid 用作基质辅助激光解吸电离-飞行时间质谱 (MALDI-TOF) 分析的基质，可以促进肽离子化。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Halestrap, A.P.The mitochondrial pyruvate carrier: Kinetics and specificity for substrates and inhibitorsBiochem. J.148(1),85-96(1975)
Watanabe, M., Terasawa, K., Kaneshiro, K., et al.Improvement of mass spectrometry analysis of glycoproteins by MALDI-MS using 3-aminoquinoline/α-cyano-4-hydroxycinnamic acidAnal. Bioanal. Chem.405(12),4289-4293(2013)
Yang, H., Wan, D., Song, F., et al.α-Cyano-4-hydroxycinnamic acid, sinapinic acid, and ferulic acid as matrices and alkylating agents for matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of cysteine-containing peptidesRapid Commun. Mass Spectrom.27(12),1410-1412(2013)
