MYCi975
Cat. No.:YN270205
CAS No. :2289691-01-4
产品名称: | MYCi975 |
CAS No.: | 2289691-01-4 |
Chemical Name: | |
Synonyms: | NUCC-0200975 |
分子量: | 561.30 |
分子式: | C₂₅H₁₆Cl₂F₆N₂O₂ |
SMILES: | OC1=C(C2=CC(C(F)(F)F)=NN2C)C=CC(OCC3=CC=C(Cl)C=C3)=C1C4=CC=C(Cl)C(C(F)(F)F)=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MYCi975 (NUCC-0200975) 是一种具有口服活性的MYC抑制剂,它破坏 MYC/MAX 相互作用,促进 MYC T58 磷酸化和 MYC 降解,并损害 MYC 驱动的基因表达。MYCi975 (NUCC-0200975) 具有很强的抗肿瘤作用和良好的耐受性,增加肿瘤免疫细胞浸润,增强肿瘤对抗 PD1 免疫研究的敏感性。 |
IC50和靶点: | |
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Clinical Trial: | |
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