KJ Pyr 9
Cat. No.:YN270389
CAS No. :581073-80-5
产品名称: | KJ Pyr 9 |
CAS No.: | 581073-80-5 |
Chemical Name: | 4-[2-(2-furanyl)-6-(4-nitrophenyl)-4-pyridinyl]-benzamide |
Synonyms: | KJ Pyr9 |
分子量: | 385.37 |
分子式: | C₂₂H₁₅N₃O₄ |
SMILES: | O=C(N)C1=CC=C(C2=CC(C3=CC=CO3)=NC(C4=CC=C([N+]([O-])=O)C=C4)=C2)C=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | KJ Pyr 9 是MYC的抑制剂。体外实验中, KJ Pyr 9 抑制 MYC 的Kd值为 6.5±1.0 nM。 |
IC50和靶点: | |
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Hart, J.A., Garner, A.L., Yu, J., et al.Inhibitor of MYC identified in a Kröhnke pyridine libraryProc. Natl. Acad. Sci. USA111(34),12556-12561(2014)
Raffeiner, P., Röck, R., Schraffl, A., et al.In vivo quantification and perturbation of Myc-Max interactions and the impact on oncogenic potentialOncotarget5(19),8869-8878(2014)