Stauprimide
Cat. No.：YN270571
| 产品名称: | Stauprimide |
| CAS No.: | 154589-96-5 |
| Chemical Name: | N-[(9S,10R,11R,13R)-2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-1,3-dioxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl]-N-methyl-benzamide |
| Synonyms: | N-Benzoyl-7-oxo Staurosporine |
| 分子量: | 584.62 |
| 分子式: | C₃₅H₂₈N₄O₅ |
| SMILES: | C[C@@]([C@@H]1OC)(O[C@](N2C3=CC=CC=C43)([H])C[C@H]1N(C)C(C5=CC=CC=C5)=O)N6C(C2=C4C(C7=O)=C8C(N7)=O)=C8C9=C6C=CC=C9 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Stauprimide 是一种促进胚胎干细胞 (ESC) 分化的星形孢菌素类似物。Stauprimide 与 MYC 转录因子NME2结合并阻断其在 ESC 中的核定位，导致 MYC 转录的下调, 是一种非广谱抑制剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Zhu, S., Wurdak, H., Wang, J., et al.A small molecule primes embryonic stem cells for differentiationCell Stem Cell4(5),416-426(2009)
