Nucleozin
Cat. No.:YN250834
CAS No. :341001-38-5
产品名称: | Nucleozin |
CAS No.: | 341001-38-5 |
Chemical Name: | [4-(2-chloro-4-nitrophenyl)-1-piperazinyl](5-methyl-3-phenyl-4-isoxazolyl)-methanone |
Synonyms: | [4-(2-氯-4-硝基苯基)-1-哌嗪基](5-甲基-3-苯基-4-异噁唑基)-甲酮 |
分子量: | 426.85 |
分子式: | C₂₁H₁₉ClN₄O₄ |
SMILES: | CC1=C(C(C2=CC=CC=C2)=NO1)C(N3CCN(C4=C(C=C(C=C4)[N+]([O-])=O)Cl)CC3)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Nucleozin 是influenza A病毒感染的有效抑制剂,能诱导核蛋白 (NP) 聚集体的形成并抑制其核聚集体的积聚,从而导致病毒复制停止。Nucleozin 以纳摩尔 EC50抑制甲型流感病毒体外复制。 |
IC50和靶点: | |
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Kao, R.Y., Yang, D., Lau, L.-S., et al.Identification of influenza A nucleoprotein as an antiviral targetNat. Biotechnol.28(6),600-605(2010)