SP-100030
Cat. No.：YN410014
CAS No. ：154563-54-9
| 产品名称: | SP-100030 |
| CAS No.: | 154563-54-9 |
| Chemical Name: | N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide |
| Synonyms: | SP 100030,SP100030 |
| 分子量: | 437.65 |
| 分子式: | C₁₄H₅ClF₉N₃O |
| SMILES: | FC(F)(F)C1=CC(C(F)(F)F)=CC(NC(C2=CN=C(Cl)N=C2C(F)(F)F)=O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SP-100030 是一种有效的NF-κB和激活蛋白-1(AP-1)双抑制剂 (IC50分别为 50 和 50 nM)。SP-10003 抑制 Jurkat和其他T细胞系产生的 IL-2、IL-8 和 TNF-α 的产生。SP-100030 降低小鼠胶原性关节炎 (CIA)。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Palanki, M.S.S.
et al.: J. Med. Chem., 43, 3995 (2000)
