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Zingerone

Cat. No.:YN410061

  • CAS No. :122-48-5

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Zingerone
      CAS No.: 122-48-5
      Chemical Name: 4-(4-hydroxy-3-methoxyphenyl)-2-butanone
      Synonyms:姜酮; Vanillylacetone; Gingerone
      分子量:194.23
      分子式:C₁₁H₁₄O₃
      SMILES:COC1=C(O)C=CC(CCC(C)=O)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Zingerone (Vanillylacetone) 是一种无毒的甲氧基苯酚,从生姜中得到,具有抗炎、抗糖尿病、抗脂质过敏、抗腹泻、抗痉挛和抗肿瘤等活性。Zingerone 能够缓解氧化应激和炎症,下调 NF-κB 介导的信号通路。Zingerone 作为抗有丝分裂剂,能够抑制神经母细胞瘤的生长。
      IC50和靶点:
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    • Nomura, H.LXIV.—The pungent principles of ginger. Part I. A new ketone, zingerone (4-hydroxy-3-methoxyphenylethyl methyl ketone) occurring in gingerJ. Chem. Soc.111,769-776(1917)

      Ahmad, B., Rehman, M.U., Amin, I., et al.A review on pharmacological properties of zingerone (4-(4-hydroxy-3-methoxyphenyl)-2-butanone)ScientificWorldJournal2015:816364,(2015)

      Manjunatha, J.R., Bettadaiah, B.K., Negi, P.S., et al.Synthesis of quinoline derivatives of tetrahydrocurcumin and zingerone and evaluation of their antioxidant and antibacterial attributesFood Chem.136(2),650-658(2013)

      Hemalatha, K.L., and Prince, P.S.M.Anti-inflammatory and anti-thrombotic effects of zingerone in a rat model of myocardial infarctionEur. J. Pharmacol.791,595-602(2016)

      Vinothkumar, R., Vinothkumar, R., Sudha, M., et al.Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in ratsEur. J. Cancer Prev.23(5),361-371(2014)

      Chen, J.-C., Huang, L.-J., Wu, S.-L., et al.Ginger and its bioactive component inhibit enterotoxigenic Escherichia coli heat-labile enterotoxin-induced diarrhea in miceJ. Agric. Food Chem.55(21),8390-8397(2007)

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