CID-2858522
Cat. No.：YN410068
| 产品名称: | CID-2858522 |
| CAS No.: | 758679-97-9 |
| Chemical Name: | 1-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-[2-[(3-hydroxypropyl)amino]-5,6-dimethyl-1H-benzimidazol-1-yl]-ethanone |
| Synonyms: | CID-2858522;1-(3,5-Di-tert-butyl-4-hydroxyphenyl)-2-(2-(3-hydroxypropylamino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone;1-(3,5-ditert-butyl-4-hydroxyphenyl)-2-[2-(3-hydroxypropylamino)-5,6-dimethylbenzimidazol-1-yl]ethanone;1-[3,5-Bis(1,1-diMethyleth |
| 分子量: | 465.63 |
| 分子式: | C₂₈H₃₉N₃O₃ |
| SMILES: | CC1=C(C)C=C2N=C(NCCCO)N(CC(C3=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C3)=O)C2=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CID-2858522 是一种高效的选择性抗原受体介导的NF-κB抑制剂，IC50为 70 nM。 |
| IC50和靶点: | [{name:"NF-κB:70 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Peddibhotla, S., Shi, R., Khan, P., et al.Inhibition of protein kinase C-driven nuclear factor-κB activation: Synthesis, structure-activity relationship, and pharmacological profiling of pathway specific benzimidazole probe moleculesJ. Med. Chem.53(12),4793-4797(2010)
