Dihydroartemisinin
Cat. No.:YN410093
产品名称: | Dihydroartemisinin |
CAS No.: | 71939-50-9 |
Chemical Name: | (3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol |
Synonyms: | 双氢青蒿素; Dihydroqinghaosu; β |
分子量: | 284.35 |
分子式: | C₁₅H₂₄O₅ |
SMILES: | O[C@@H]1[C@H](C)[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Dihydroartemisinin是一种有效的抗疟疾 (anti-malaria) 药物。 |
IC50和靶点: | |
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Dai, X., Zhang, X.C., W., Chen, Y., et al.Dihydroartemisinin: A potential natural anticancer drugInt. J. Biol. Sci.17(2),603-622(2021)
Mbye, H., Bojang, F., Jawara, A.S., et al.Tolerance of gambian Plasmodium falciparum to dihydroartemisinin and lumefantrine detected by ex vivo parasite survival rate assayAntimicrob. Agents Chemother.65(1),e00720-00720(2020)
Su, Y., Zhao, D., Jin, C., et al.Dihydroartemisinin induces ferroptosis in HCC by promoting the formation of PEBP1/15-LOOxid. Med. Cell. Longev.,3456725(2021)
Chen, Y., Yan, Y., Liu, H., et al.Dihydroartemisinin ameliorates psoriatic skin inflammation and its relapse by diminishing CD8+ T-cell memory in wild-type and humanized miceTheranostics10(23),10466-10482(2020)