Baicalin
Cat. No.：YN410095
CAS No. ：21967-41-9
| 产品名称: | Baicalin |
| CAS No.: | 21967-41-9 |
| Chemical Name: | 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid |
| Synonyms: | 黄芩苷; Baicalein 7-O-β-D-glucuronide |
| 分子量: | 446.36 |
| 分子式: | C₂₁H₁₈O₁₁ |
| SMILES: | O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=C(O)C(O)=C3C(C=C(C4=CC=CC=C4)OC3=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Baicalin 是一种从Scutellaria baicalensis中分离出来的类黄酮糖苷。Baicalin 降低NF-κB表达。 |
| IC50和靶点: | |
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Bai, J., Wang, Q., Qi, J., et al.Promoting effect of baicalin on nitric oxide production in CMECs via activating the PI3K-AKT-eNOS pathway attenuates myocardial ischemia–reperfusion injuryPhytomedicine63,153035(2019)
Ke, M., Zhang, Z., Xu, B., et al.Baicalein and baicalin promote antitumor immunity by suppressing PD-L1 expression in hepatocellular carcinoma cellsInt. Immunopharmacol.75,105824(2019)
Shah, M.-A., Park, D.-J., Kang, J.-B., et al.Baicalin attenuates lipopolysaccharideinduced neuroinflammation in cerebral cortex of mice via inhibiting nuclear factor kappa B (NF-κB) activationJ. Vet. Med. Sci.81(9),1359-1367(2019)
Wang, W., Zheng, J., Cui, N., et al.Baicalin ameliorates polycystic ovary syndrome through AMP-activated protein kinaseJ. Ovarian Res.12(1),109(2019)
Lu, Y., Sun, G., Yang, F., et al.Baicalin regulates depression behavior in mice exposed to chronic mild stress via the Rac/LIMK/cofilin pathwayBiomed. Pharmacother.116,109054(2019)
