Rhynchophylline
Cat. No.：YN410101
CAS No. ：76-66-4
| 产品名称: | Rhynchophylline |
| CAS No.: | 76-66-4 |
| Chemical Name: | (αE,1′R,6′R,7′S,8′aS)-6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, methyl ester |
| Synonyms: | 钩藤碱 |
| 分子量: | 384.47 |
| 分子式: | C₂₂H₂₈N₂O₄ |
| SMILES: | O=C(NC1=C2C=CC=C1)[C@]32[C@@](C[C@H](/C(C(OC)=O)=C\OC)[C@@H](CC)C4)([H])N4CC3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 钩藤碱 (Rhyncholphylline)是从钩藤中分离到的一种生物碱类化合物，具有很高的生物活性，被广泛用于抗炎、神经保护等方面的研究。 |
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Chen, C.X., Jin, R.M., Li, Y.K., et al.Inhibitory effect of rhynchophylline on platelet aggregation and thrombosisZhongguo Yao Li Xue Bao13(2),126-130(1992)
Yoo, J.H., Ha, T.-W., Hong, J.T., et al.Rhynchophylline, one of major constituents of Uncariae Ramulus et Uncus enhances oentobarbital-induced sleep behaviors and rapid eye movement sleep in rodentsNat. Prod. Sci.22(4),263(2016)
Wang, L., Wang, Y., Chen, Y., et al.Rhynchophylline ameliorates cerebral ischemia by improving the synapticvplasticity in a middle cerebral artery occlusion induced stroke modelEur. J. Pharmacol.940,175390(2023)
Jiang, P., Chen, L., Xu, J., et al.Neuroprotective effects of rhynchophylline against Aβ1-42-induced oxidative stress, neurodegeneration, and memory impairment via Nrf2-ARE activationNeurochem. Res.46(9),2439-2450(2021)
